Heather Sullivan had spent years dealing with her son Sawyer’s eczema. From a young age, his body would be covered in itchy rashes that were painful and uncomfortable. They tried various treatments, including steroid creams and bleach baths, but nothing seemed to work. At 15 months, Sawyer was even put on a powerful immunosuppressant, which helped temporarily but came with dangerous side effects.
Then, a new eczema drug called Dupixent entered the picture. Within a week, Sawyer’s symptoms improved drastically. This marked a turning point in eczema treatment, with a range of new options becoming available. These treatments target the underlying biological pathway of eczema and have proven to be highly effective.
Eczema, or atopic dermatitis, affects a significant portion of the population, with about 10 percent of Americans suffering from the condition. For those with moderate to severe eczema, it can have a major impact on daily life. Traditional treatments like topical steroids can provide some relief, but they also come with unwanted side effects. The new drugs, on the other hand, target specific parts of the immune system with fewer drawbacks.
These breakthrough treatments were developed through years of research and serendipity. They were initially designed for other conditions but were repurposed when their effectiveness against eczema was discovered. This represents a broader revolution in treating inflammatory disorders, with these drugs being used for various conditions.
While these new drugs may have some side effects, they are generally considered safer and more effective than traditional options. Some physicians may still be hesitant to prescribe them, but overall, they offer a better alternative. However, cost and insurance coverage can be significant barriers to accessing these treatments.
In the future, topical JAK inhibitors could become the go-to treatment for mild eczema as well, providing a safer option compared to topical steroids. However, at present, steroids remain widely used due to their affordability and availability.
Overall, these new treatments have significantly improved the lives of those with moderate to severe eczema. With further research and advancements, the hope is that they will become more accessible to all patients, regardless of the severity of their condition.
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