Emily Wright, an elementary school teacher from Toronto, began using the drug Ozempic in 2018 to manage her Type 2 diabetes and control her food cravings. She experienced significant weight loss as a result, but also suffered from constant vomiting and nausea. Despite these side effects, she stayed on the medication and lost over 80 pounds in one year.
However, after two years, her symptoms worsened and she was hospitalized for severe nausea and dehydration. She was diagnosed with gastroparesis, a condition that causes stomach paralysis. Her new doctor suggested that Ozempic may be connected to her symptoms and advised her to stop taking the drug. Since then, Wright’s symptoms have not improved, and she has had to take a leave of absence from work. She now requires medication and daily nausea medication to manage her condition.
Although nausea and vomiting are common side effects of Ozempic, extreme reactions like Wright’s are rare. The drug is primarily used to treat Type 2 diabetes and is sometimes prescribed off-label for weight loss. The full list of side effects includes nausea, vomiting, diarrhea, stomach pain, and constipation, but stomach paralysis is not mentioned.
Dr. Ravi Retnakaran, an endocrinologist at the University of Toronto, explained that while gastrointestinal side effects are common with drugs like Ozempic, it is puzzling that Wright continued to experience symptoms even after stopping the medication. He also noted that diabetes itself can cause gastrointestinal issues.
Ozempic is a GLP-1 agonist medication used for Type 2 diabetes and off-label for weight loss. It mimics a gut hormone and helps regulate blood glucose levels, suppress appetite, and promote weight loss. Despite its success, nausea remains a common side effect. Novo Nordisk, the company that manufactures Ozempic, takes reports of adverse events seriously and acknowledges that gastrointestinal issues are a known side effect of GLP-1 agonists.
Retnakaran believes that drugs like Ozempic have shown significant benefits for his patients, including improved glucose control, reduced cardiovascular and mortality risk for kidney disease, and substantial weight loss. However, he acknowledges that some patients may not tolerate the medication due to side effects like nausea.
Emily Wright advises people to carefully consider the risks and benefits of medications like Ozempic and to advocate for themselves if they experience abnormal side effects. Despite her own experience, she acknowledges that the drug may have benefited other individuals.
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