Improving Memory of Alzheimer’s Patients: Promising Potential of Insulin Nasal Spray

Spraying insulin hormone into the nose has shown potential in improving memory for individuals with Alzheimer’s disease. According to a recent study, patients who used an insulin nasal spray had better recall abilities for word lists and object names. The hormone is believed to be absorbed into the bloodstream after being sprayed into the nostrils, where it can then clear amyloid plaque, the harmful deposits associated with Alzheimer’s disease, in the brain. Alzheimer’s disease is closely linked to the buildup of amyloid plaque. While there is currently no cure for the disease, new drugs like donanemab have been in the spotlight for their potential to slow down the disease’s progression by targeting amyloid. However, these drugs can have significant side effects such as bleeding or brain swelling. Researchers have turned their attention to insulin as a potential treatment since it has been observed that individuals with diabetes, who often have insulin resistance, are at a higher risk of developing Alzheimer’s disease.

Inhaled insulin has been the focus of numerous studies over the past decade to combat dementia. Although it was approved as a diabetes treatment in the UK in 2006, it was later withdrawn due to low uptake. Furthermore, a recent study by the University of California San Francisco found that a jab containing an anti-aging protein called klotho, which helps combat cell damage, improved memory and cognition in older monkeys. Lower levels of klotho have been found in people with dementia. A meta-analysis conducted by Toronto University in Canada pooled data from 11 studies involving over 1,000 Alzheimer’s patients and individuals with mild cognitive impairment, a precursor to dementia. The study found that patients treated with an insulin nasal spray for up to four months performed significantly better on memory and cognitive tasks compared to individuals given a placebo. These tasks were part of the Alzheimer’s Disease Assessment Scale, which evaluates the impact of the disease on the brain. Researchers believe that inhaling insulin influences the clearance of harmful brain deposits.

Dr. Richard Oakley, associate director of research and innovation at the Alzheimer’s Society, acknowledges that this research showed a small improvement in memory and thinking skills with insulin nasal spray. However, he emphasizes the need for further large clinical trials to definitively establish its effectiveness for individuals with Alzheimer’s disease.

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Denial of responsibility! Vigour Times is an automatic aggregator of Global media. In each content, the hyperlink to the primary source is specified. All trademarks belong to their rightful owners, and all materials to their authors. For any complaint, please reach us at – [email protected]. We will take necessary action within 24 hours.
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