Mpox, a virus that is impacting the LGBTQ+ community, continues to be a concern in California. Recent data from the state’s public health department shows an increase in mpox cases, signaling that the virus is still a threat. Additionally, research from the University of Edinburgh suggests that the virus is evolving, potentially making it more infectious.
California’s public health department reports that there are now 17 new cases of mpox each week, up from less than seven in August. To combat this increase, healthcare providers have been alerted to remain vigilant and take necessary precautions.
Previously, mpox cases were rare in the US and Europe, but a significant outbreak occurred in 2022, with a majority of cases occurring in gay and bisexual men. Although there was a decrease in cases last year, mpox infections continue to occur, particularly in California.
Dr. Tomás J. Aragón, the state’s public health director, emphasizes the importance of prevention and vaccination in combating mpox. Vaccination, preferably with a double dose of the mpox vaccine administered a month apart, is recommended to minimize the risk of severe illness.
However, there is concern as the Bay Area Reporter reveals that around 40% of individuals who received the first dose of the vaccine did not complete the two-dose series.
The San Francisco Department of Health urges individuals to complete their vaccination series, as it significantly reduces the risk of severe illness, hospitalization, and death. It is never too late to get the second dose of the vaccine.
According to the Centers for Disease Control and Prevention (CDC), there have been over 31,000 mpox cases and 55 deaths in the US since the start of the outbreak in 2022, with a notable proportion of deaths occurring in immunocompromised individuals. In 2023, there have been 935 cases reported.
Virus evolution and the need for vaccination
A report published in Science by researchers from the University of Edinburgh highlights the rapid mutation of the mpox virus. Previously, human cases of mpox were primarily due to animal transmission. However, the surge in human-to-human transmission has influenced the virus’s evolution.
The researchers have observed mutations in a specific part of the virus’s genetic code, which is targeted by an enzyme in the human immune system. This enzyme inhibits virus replication. If a mutation occurs that makes the virus more resistant to this enzyme, it could become stronger and more infectious.
Given these developments, healthcare providers emphasize the importance of both vaccine doses to minimize the risk of falling ill. Consult your healthcare provider to ensure you are fully protected against mpox.
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