Study reveals nearly 800,000 deaths and disabilities in the US each year caused by errors in disease diagnosis

Misdiagnoses in the United States result in a significant number of deaths and disabilities, according to a recent report from Johns Hopkins School of Medicine in Maryland. The study revealed that approximately 795,000 Americans suffer from permanent disability or die each year due to misdiagnoses. The research, published in The BMJ, a reputable medical trade journal, highlights the top five misdiagnosed conditions: stroke, sepsis, pneumonia, venous thromboembolism, and lung cancer. These conditions collectively account for 38.7% of all misdiagnosed cases. Surprisingly, over half of all serious harm cases can be attributed to just 15 dangerous diseases, which suggests that this issue may be more manageable than previously anticipated.

The study’s co-author, Dr. David Newman-Toker, a professor of neurology at the Johns Hopkins University School of Medicine, explained how the team determined the number of affected individuals. They used a straightforward method involving calculating the total number of cases for dangerous diseases such as heart attacks, strokes, infections, vascular events, and cancer. They then multiplied this number by the error rate for each condition and the associated risk of harm. Despite the valuable insights provided by these findings, Newman-Toker noted that the field of public health dedicated to preventing misdiagnoses is severely underfunded.

To gather data for their research, the team relied on various sources, including the National Inpatient Sample, national cancer registries, and systematic reviews. They used nine different approaches to ensure the validity of their numbers. The total of nearly 800,000 harmful outcomes did not come as a surprise to the researchers, as diagnostic errors have long been known as a significant source of harm in the medical field. However, what was unexpected was the small number of diseases responsible for the majority of errors. Just 15 diseases accounted for half of all serious harms, with the top five conditions representing nearly 40% of cases.

Newman-Toker believes that patients can play a crucial role in preventing misdiagnoses. He recommends that patients come prepared to appointments by asking questions and staying alert. Patients should inquire about the worst possible diagnosis and why it may not be accurate. It is also important for patients to be proactive in ensuring the accuracy of their diagnosis rather than focusing solely on medication changes. By following these steps and remaining vigilant, patients can protect themselves and contribute to reducing the occurrence of misdiagnoses. However, it should be noted that the sector of public health dedicated to addressing this issue remains grossly underfunded.

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