A groundbreaking advancement in hair growth research has been announced by a biopharmaceutical company in San Diego. According to Amplifica Holdings Group, researchers from the University of California have discovered a molecule called osteopontin that is associated with faster hair growth. The findings, which were published in the journal Nature last month, revealed that injectable osteopontin stimulated hair follicle stem cells and generated new hair growth in skin grafts. This discovery, inspired by the natural hair growth seen in hairy moles, could potentially lead to the development of effective treatments for hair loss. Maksim Plikus, Amplifica’s chief scientific officer, expressed that this research offers a promising solution that physicians and patients have been seeking, as current hair loss treatments are not considered true solutions. Clinical trials for this new approach are on the horizon. In hair loss cases, essential signaling proteins in hair follicles that stimulate hair stem cells gradually decrease, causing stem cells to remain dormant for extended periods. Therefore, injecting signaling proteins into the scalp to activate dormant hair stem cells is seen as an efficient strategy to combat hair loss. The molecule osteopontin, found in higher levels in hairy moles, has been found to stimulate hair follicle stem cells. However, further clinical studies are necessary to evaluate the effectiveness of this treatment in humans. Amplifica’s initial study, focusing on the safety and tolerability of osteopontin, is scheduled to commence this summer.
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