The Impact of Oestrogen Exposure: How Women with Multiple Children Lower Dementia Risk, According to Research









Women who have had several children could be at a reduced risk of dementia, research suggests.

Experts have discovered that higher exposure to estrogen throughout a woman’s life could lead to a healthier brain.

Those with a longer ‘reproductive lifespan’, or who have had several children, accumulate a higher exposure to the hormone.

This appears to lead to a lower risk of cerebral small vessel disease – a condition that results from damage to small blood vessels in the brain and is linked to cognitive impairment and dementia.

Researchers analyzed 9,000 postmenopausal women with an average age of 64 living in the UK.

The Impact of Oestrogen Exposure: How Women with Multiple Children Lower Dementia Risk, According to Research

Women who have had several children could be at a reduced risk of dementia, research suggests (stock image)

Participants answered questions on reproductive health including their age at their first period, when they started menopause, and their number of pregnancies.

They also had brain scans to look for cerebral small vessel disease.

The scientists calculated lifetime hormone exposure by adding the number of years women were pregnant to the duration of their reproductive lifespan, which is the number of years between first menstruation and menopause.

Reference

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