In a groundbreaking medical achievement, surgeons in Oxford have successfully completed a womb transplant procedure between two sisters, marking a significant advancement in fertility treatment. The surgery, performed as part of the U.K.’s living donor program, holds immense potential for expanding childbirth options.
The procedure involved a 40-year-old living donor sister who had already given birth to two children. She generously donated her womb to her 34-year-old sister, who was born without a fully developed womb. Both sisters have chosen to remain anonymous.
The surgical details of the transplant were published in the British Journal of Obstetrics and Gynaecology, highlighting the extensive efforts and the involvement of more than 30 staff members. The transplant implantation alone took over nine hours, and the entire process lasted around 17 hours. Remarkably, both women recovered well and were discharged from the hospital after ten days of care.
The recipient of the womb transplant expressed her overwhelming happiness and gratitude for the successful treatment, as reported by Womb Transplant U.K., the charity that funded the procedure. She now plans to undergo in vitro fertilization (IVF) in the hope of conceiving two children of her own.
Prior to the transplant, the recipient sister underwent various fertility treatments, including egg stimulation and intracytoplasmic sperm injection (ICSI) to produce embryos. If everything progresses smoothly, the embryo transfer is expected to take place later this year.
The development of womb transplant procedures has been a focus of research for the past 25 years, according to the NHS. Surgeon Richard Smith, one of the leaders of the surgical team, expressed gratitude towards the donor sister and the charity Womb Transplant U.K. for their contributions and support.
Smith also emphasized that future womb transplants will depend on suitable donors and the availability of funding. He expressed hope that they will be able to help more women born without or with underdeveloped wombs in the near future.
This successful womb transplant in the U.K. adds to the approximately 100 transplants performed globally, with an estimated 50 babies born as a result. The first successful womb transplant took place in Sweden in 2013.
Looking ahead, another womb transplant is already scheduled for this fall in the U.K. Furthermore, several other patients are in the preparation stages for the same treatment, with brain-dead and living donors ready to participate.
The recipient of this particular transplant was born with Mayer-Rokitansky-Küster-Hauser syndrome (MRKH), a rare condition in which the womb is absent. MRKH affects around one in 5,000 live female births, and many women may lose their wombs due to cancer or conditions like endometriosis.
In conclusion, the successful womb transplant in Oxford represents a major breakthrough in medical science and offers hope to women facing fertility challenges. With ongoing research and the support of donors and charities, this procedure has the potential to transform the lives of many women in the future.
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