- A study conducted by researchers tested the efficacy of a prostate cancer drug called proxalutamide
- The study revealed that the drug effectively limited the invasion of cells by the Covid virus
A study suggests that a prostate cancer drug could potentially prevent vulnerable individuals from contracting Covid-19.
Researchers at The University of Michigan Medical School conducted a study where they tested the effect of a new and promising cancer treatment called proxalutamide on animal cells infected with Covid-19.
The study found that proxalutamide limited the invasion of cells by the virus.
Furthermore, when the researchers combined proxalutamide with another licensed Covid drug called remdesivir, the virus was completely blocked.
Subsequent studies on mice showed that this drug combination reduced the risk of severe Covid-related internal inflammation and decreased mortality.
A prostate cancer drug could help stop vulnerable people becoming ill with Covid, a study suggests.
Proxalutamide works by blocking an enzyme that allows viral cells to enter healthy lung cells and multiply.
In the treatment of prostate cancer, it inhibits the activity of androgens, such as testosterone, which can stimulate tumor growth.
According to the latest data from the government, approximately 70 people succumb to Covid every week. Currently, around 2,200 individuals in the UK are hospitalized due to the virus, with 79 on ventilators.
While several treatments are now available, they do not work for everyone, especially the most vulnerable individuals, including those with blood cancer and organ transplant recipients.
Studies have shown that proxalutamide can effectively control the disease in two-thirds of patients, although it has not yet been approved in the UK.
Commenting on the new findings, Arul Chinnaiyan, director of the Michigan Center for Translational Pathology and co-author of the study, said, “The idea is that proxalutamide could work as a combined therapy with remdesivir, attacking the virus from multiple angles, similar to how we use combination therapy for HIV infection.”
Early in the pandemic, it was suggested that there was a link between the virus and male hormones, as the majority of deaths occurred in men.
The researchers state that their study provides evidence of a mysterious link between androgens and the virus, although the intricacies of this
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