Can Switching from Drip Coffee to Espresso “Treat Alzheimer’s”? Promising Results from Lab Study
Coffee enthusiasts may have more to rejoice about than just a caffeine kick, as research reveals that compounds found in a shot of espresso could potentially prevent the development of Alzheimer’s.
According to a recent study, a shot of coffee has been shown to inhibit a process believed to be involved in the onset of Alzheimer’s disease.
While the exact mechanisms behind Alzheimer’s and dementia remain unclear, the protein tau is thought to play a significant role.
In healthy individuals, tau proteins help stabilize brain structures, but in Alzheimer’s patients, these proteins can clump together into thread-like structures called fibrils.
Research now shows that compounds found in espresso can inhibit a process that is believed to be involved in the onset of Alzheimer’s disease (stock image)
Some researchers believe that preventing the clumping of tau proteins could alleviate Alzheimer’s symptoms or even prevent the disease from developing altogether.
Mariapina D’Onofrio, a biologist from the University of Verona in Italy, stated, “Espresso coffee is a widely known beverage consumed worldwide, and its popularity stems from its delightful taste. Recent studies indicate that when consumed moderately, espresso coffee can have positive effects on human health due to its biological properties. Numerous studies have reported that moderate to high coffee consumption can exert a neuroprotective effect against two common neurodegenerative diseases: Parkinson’s and Alzheimer’s.”
To investigate further, D’Onofrio and her team incubated espresso extracts alongside a shortened form of the tau protein in a lab for up to 40 hours.
The researchers discovered that as the concentration of espresso extract increased, the tau fibrils remained shorter and did not form larger “tangles”. These shortened fibrils were found to be non-toxic to human cells.
The team also noted that many compounds found in coffee, such as caffeine and genistein, can cross the blood-brain barrier and deliver protective effects.
In their article published in the Follow Google News
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