Other Cabinet members will now be evaluating if they still have faith in the PM. Here’s how they have responded so far:
Liz Truss, Foreign Secretary
A source told the Telegraph that Liz Truss is “100 per cent behind the Prime Minister”.
Alister Jack, Scottish Secretary
Reports suggest Mr Jack is staying as Scottish Secretary and still supports the PM.
Jacob Rees-Mogg, Brexit Opportunities Minister
“The PM won a mandate from the British people and that is more powerful than Cabinet ministers resigning,” said Mr Rees-Mogg.
The Brexit Opportunities Minister told Sky News: “The Prime Minister won a large mandate in a general election, a vote of the British people, and that should not be taken away from him because a number of people resign.”
He said that “losing chancellors is something that happens”.
“The Prime Minister won the vote. The thing about democracy is if you win the vote, you’ve won and that I think is fundamental,” he said, referencing the recent confidence vote in Mr Johnson.
He said that it is the Prime Minister who appoints Cabinet ministers and is “not someone who is brought down by Cabinet ministers”.
Suella Braverman, Attorney General
The Attorney General is remaining in Government, sources have told Sky News.
Anne Marie-Trevelyan, Trade Secretary
Source close to the Trade Secretary told CityAM she is “going nowhere”.
Priti Patel, Home Secretary
An ally of Ms Patel said “she’s staying”.
Kwasi Kwarteng, Business Secretary
Sources told Sky News Mr Kwarteng is staying in Government.
Dominic Raab, Justice Secretary
A source close to Mr Raab said he was “loyal” to Mr Johnson.
Ben Wallace, Defence Secretary
A source close to Ben Wallace, who has been tipped as a potential successor to Mr Johnson, said: “The Defence Secretary is not resigning.”
Brandon Lewis, Northern Ireland Secretary
Brandon Lewis also has “no plans to resign”, according to the Guardian.
Nadine Dorries, Culture Secretary
The Culture Secretary tweeted her support for Mr Johnson, below.