Ketamine May Cause Brain Changes Similar to Schizophrenia, Study Finds
In one of the first long-term studies, researchers in New York City tested the effects of ketamine on the brain and found that repeated exposure to the drug led to structural rewiring in areas that produce dopamine, a neurotransmitter associated with memory, mood, sleep, learning, and movement. These changes were similar to those observed in conditions like schizophrenia.
With this study in mind, the researchers hope that more targeted treatment for mental health can be developed, aiming at particular dopamine-producing brain regions to minimize unintended side effects.
Actress Chrissy Teigen recently shared her experience with ketamine therapy, revealing hallucinations of her late son, Jack. However, caution should be exercised as ketamine is not approved by the FDA for mental health treatment.
Ketamine, originally developed as an anesthetic, has morphed into a street drug and treatment for various mental health conditions despite not being FDA-approved. Clinics that offer ketamine treatment for depression and PTSD are increasingly popular, but the long-term effects are still unknown.
While evidence suggests that off-label ketamine could alleviate depression symptoms, more research is needed. The study team hopes their findings can lead to safer and more targeted clinical therapies.
