Bacteria living on ocean plastic pollution could produce ANTIBIOTICS capable of protecting humans against drug-resistant superbugs, scientists claim
- Ocean microplastics provide a surface for antibiotic-producing bacteria to grow
- Scientists from San Diego isolated five bacteria from pieces of ocean plastic
- They found they were receptive against some antibiotic-resistant bacteria
- They could be utilised as novel antibiotics against future ‘superbugs’
Plastic waste is being discovered in increasingly remote locations across the world, from fresh Antarctic snow to the mountain air above the Pyrenees.
As a result, scientists are working hard to find new ways to tackle the global problem of plastic pollution, like with plastic-eating worms or robots that turn it into designer objects.
However, a new area of research is looking at how bacteria living on plastic pollution floating in the ocean could provide a new source of antibiotics.
Researchers from National University in San Diego have isolated five antibiotic-producing bacteria from pieces of ocean plastic, and tested them against a variety of bacterial targets.
They found that these antibiotics were effective against common bacteria as well as two antibiotic-resistant strains, known as ‘superbugs’.
Researchers from National University in San Diego isolated five antibiotic-producing bacteria from pieces of ocean plastic, and tested them against bacterial targets (stock image)
Microplastics (pictured) have previously been discovered in Antarctic sea ice and surface water but researchers said this is the first time they have been reported in fresh snowfall
Bacillus subtilis strains have been reported to produce ribosomal antibiotics (stock image)
WHAT ARE MICROPLASTICS?
Microplastics are plastic particles measuring less than five millimetres (0.2 inches)
Each year, tonnes of plastic waste fails to get recycled and dealt with correctly, which can mean they end up in marine ecosystems
Although it’s unclear exactly how they end up in the water, microplastics may enter through simple everyday wear and tear of clothing and carpets
Plastics don’t break down for thousands of years and it is estimated that there are already millions of items of plastic waste in the oceans
Scientists warn microplastics are so small they could penetrate organs
Creatures of all shapes and sizes have been found to have consumed the plastics, whether directly or indirectly
Previous research has also revealed microplastics absorb toxic chemicals, which are then released in the gut of animals
It is estimated that between 5 and 13 million metric tons of plastic pollution enter the oceans each year.
This ranges from large floating debris to microplastics as a result of the waste breaking down.
Microbes can use the plastic as a surface upon which it can multiply and form entire ecosystems.
While it is a concern that antibiotic-resistant bacteria may form upon the plastic, some of the microbes may be able to produce novel antibiotics.
These could be utilised to fight strains of antibiotic-resistant superbugs in the future.
Antibiotic-producing bacteria tend to exist in competitive natural environments, as they create the antibiotics to fend off competitors for resources and space.
Researchers incubated high- and low-density polyethylene plastic, (the type used to make plastic bags), in water near Scripps Pier in La Jolla, California, for 90 days.
They then isolated five antibiotic-producing bacteria from the ocean plastic, including strains of Bacillus, Phaeobacter and Vibrio.
Next they tested the bacterial ‘isolates’ against a variety of Gram-positive and negative targets.
Gram-positive bacteria have a thicker cell wall than gram-negative bacteria, and are often more receptive to certain cell-wall targeting antibiotics.
They found their isolates to be effective against common bacteria as well as two antibiotic-resistant strains.
Andrea Price, the study’s lead author, said: ‘Considering the current antibiotic crisis and the rise of superbugs, it is essential to look for alternative sources of novel antibiotics,
‘We hope to expand this project and further characterise the microbes and the antibiotics they produce.’
The study was conducted in in collaboration with the Scripps Institution of Oceanography and was part of a STEM education project funded by the National Science Foundation.
The results from this initial phase of research were presented at the American Society for Microbiology’s conference in Washington DC last week.
Microplastics enter the environment through a variety of means. If entering waterways, they can be ingested by seafood or absorbed by plants to end up in our food
DISEASE-CAUSING PARASITES COULD BE ‘HITCHHIKING’ ON MICROPLASTICS, STUDY WARNS
Scientists at the University of California have found that disease-causing parasites could be pouring into oceans and infecting humans and wildlife after hitching a ride on microplastics
They found three different pathogens adhere to surfaces of microplastics – tiny plastic pieces under 0.2 of an inch (5mm) in diameter
These pathogens form a biofilm – a slimy layer made from a community of microbes – making them ultra-resilient to any rough waters
By ‘hitchhiking’ on microplastics, harmful microbes can disperse throughout the ocean, reaching places a land parasite would normally never be found
This can ultimately lead to fish and seafood becoming contaminated, potentially infecting humans when caught for consumption, experts warn.
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In lab tests, California experts found three different pathogens adhere to surfaces of microplastics. Left – a piece of microplastic shown under a microscope with biofilm (fuzzy blue) and T. gondii (blue dot) and giardia (green dot) pathogens. Right – Emma Zhang, first author on the study connecting microplastics and pathogens in the ocean, works in the lab at the University of California, Davis